Prime Video’s action-packed adult animation comedy, The Second Best Hospital in the Galaxy returns for season two on May 27, 2025. We have an exclusive first look at the second season, checkout the photos, below!
From creator Cirocco Dunlap and Executive Producers Maya Rudolph and Natasha Lyonne, The Second Best Hospital in the Galaxy follows daring surgeons (and inseparable best friends) Dr. Sleech and Dr. Klak, where they frequently risk everything to take on the most dangerous cases in the universe. In Season Two of The Second Best Hospital in the Galaxy, doctors Sleech and Klak relish the fame of their recent success until a cyborg journalist starts digging a little too deep into Sleech’s past.
The series stars: Stephanie Hsu (Everything Everywhere All at Once), Keke Palmer (One of Them Days), Kieran Culkin (A Real Pain), Sam Smith (Spectre), Maya Rudolph (Loot), and Natasha Lyonne (Poker Face). The series also features Tracee Ellis Ross (American Fiction, Black-ish), Abbi Jacobson (Broad City), Andrew Dismukes (Saturday Night Live), Bowen Yang (Saturday Night Live, Fire Island), Gary Anthony Williams (Night Court), Lennon Parham (Minx), Jay Ellis (Top Gun: Maverick), Kemah Bob (Springleaf), and John Waters (Hairspray).
